Struct2Net statistics

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Citations per year

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Associated diseases

Associated diseases

Struct2Net specifications


Unique identifier OMICS_02986
Name Struct2Net
Interface Web user interface, Application programming interface
Restrictions to use None
Input data One or two amino acid sequences in FASTA format.
Input format FASTA
Output data The output gives a list of interactors if one sequence is provided and an interaction prediction if two sequences are provided.
Computer skills Basic
Stability Stable
Maintained Yes

Publications for Struct2Net

Struct2Net in publications

PMCID: 5919440
PMID: 29698482
DOI: 10.1371/journal.pone.0195545

[…] prediction methods by greedyminppi. in order to assess the usefulness of this idea, we examine a combination of greedyminppi and each of four state-of-the-art prediction methods for weighted ppis, struct2net [], ents [], pip [], and iwrap [], using four ppi datasets extracted from string [], mint [], wi-phi [], and intact []. since the four databases contain interactions with confidence score […]

PMCID: 5722940
PMID: 29222529
DOI: 10.1038/s41598-017-17633-2

[…] always lack data, are quite challenging. to closely investigate the interaction of a protein set, computational methods that include information on protein structure into prediction regime, such as struct2net and physical docking are proposed., in plants, earlier studies of ppi were limited to only a few species. the current ppi information of plants, especially cassava, has constrained choices […]

PMCID: 4548105
PMID: 26347773
DOI: 10.1155/2015/528097

[…] recall = 57.9%, and auc = 0.858. these results show the practical utility of the composite vectors method., we also applied our test dataset to a general protein-protein interaction prediction tool, struct2net [], which performs structure-based computational prediction of protein-protein interactions. it successfully predicted 7 of the 95 positive pairs and wrongly predicted 57 of the 2183 […]

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Struct2Net institution(s)
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA; Toyota Technological Institute at Chicago, Chicago, IL, USA; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA

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