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Tyrosine sulfation is a ubiquitous posttranslational modification that regulates extracellular protein-protein interactions, intracellular protein transportation modulation, and protein proteolytic process. However, identifying tyrosine sulfation sites remains a challenge due to the lability of sulfation sequences.
(Sy et al., 2012) PredSulSite: prediction of protein tyrosine sulfation sites with multiple features and analysis. Analytical Biochemistry.