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Summary statistics software tools | Genome-wide association study data analysis

Summary statistics software tools | Genome-wide association study data analysis

Imputation of individual level genotypes at untyped markers using an external reference panel of genotyped or sequenced individuals has become standard practice in genetic association studies. Direct imputation of summary statistics can also be valuable, for example in meta-analyses where individual level genotype data are not available.

Source text:
(Xu et al., 2015) DISSCO: direct imputation of summary statistics allowing covariates. Bioinformatics.

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