SurvExpress protocols

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Associated diseases

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SurvExpress specifications

Information


Unique identifier OMICS_12527
Name SurvExpress
Interface Web user interface
Restrictions to use None
Input data The main input of SurvExpress is only the biomarker gene list.
Output data The outputs included correspond to common metrics and plots used to assess the performance of survival data.
Programming languages Javascript, R
Database management system MySQL
Computer skills Basic
Version 2.0
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Victor Trevino <>

Publication for SurvExpress

SurvExpress in pipeline

2016
PMCID: 5025263
PMID: 27642640
DOI: 10.18282/amor.v2.i4.141

[…] and its significance was tested using t-test (p < 0.05). survival multivariate analysis and risk assessment for individual genes and gene signatures in human cancer data sets were performed using survexpress[] in the following datasets: ovarian (gse9891 and gse32062); head and neck (tcga and e-mtab-1328); breast (tcga and gse20685); liver (tcga and gse17856); lung adeno-carcinoma (tcga); lung […]


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SurvExpress in publications

 (78)
PMCID: 5908318
PMID: 29682217
DOI: 10.18632/oncotarget.24966

[…] samples of cancer patients [, , ]. the results indicate the potential prognostic power of this axis in predicting the progression of specific cancer type., survival data was collected from database survexpress, tcga and kaplan meier-plotter., lep: leptin. n.s.: no significance., survival data was collected from database survexpress, tcga and kaplan meier-plotter., lepr: leptin receptor. n.s.: […]

PMCID: 5875760
PMID: 29596496
DOI: 10.1371/journal.pone.0193871

[…] to the probability of breast cancer recurrence within 10 years after treatment []. additionally, we confirmed such findings in-silico for several er and ln heterogeneous populations using the survexpress tool []. this result is included in the supplementary material of survexpress. consequently, we used the recurrence score (rs) from the oncotypedx signature as an approximation […]

PMCID: 5903700
PMID: 29665325
DOI: 10.1002/cjp2.94

[…] average linkage. this was performed over genes with highest variation across patients., to assess the prognostic performance of the gene signature after identification, a prognostic index based on survexpress was used . this prognostic index is the linear component of the exponential function used to measure the level of association of the gene signature in a cox proportional hazards model. […]

PMCID: 5884658
PMID: 29644003
DOI: 10.18632/oncotarget.24594

[…] microarray was performed (figure ). the plod3 expression in gbm was higher than in non-neoplastic brain tissue. our data established plod3 overexpression in high-grade gliomas., we then used the survexpress to examine the correlation between plod3 mrna expression and survival and risk []. the survival curves and risk groups were derived from an analysis program on the basis of each glioma's […]

PMCID: 5884640
PMID: 29643985
DOI: 10.18632/oncotarget.24503

[…] and 12% (figure ). we next assessed whether the expression of taok3 and abcc1 predicted clinical outcome using patient data associated with long-term clinical follow-up. using the publicly available survexpress biomarker tool [] that stratifies pc patients into low or high-risk groups based on differential gene expression, we generated kaplan–meier survival curves using the data of taylor et al. […]


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SurvExpress institution(s)
Cátedra de Bioinformática, Tecnológico de Monterrey, Monterrey, Nuevo León, México
SurvExpress funding source(s)
Financial support from Cátedra de Bioinformática CAT220 at ITESM (Tecnológico de Monterrey) and CONACyT grants 83929 and 140601

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