SwissTargetPrediction statistics

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Citations per year

Number of citations per year for the bioinformatics software tool SwissTargetPrediction

Tool usage distribution map

This map represents all the scientific publications referring to SwissTargetPrediction per scientific context
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SwissTargetPrediction specifications


Unique identifier OMICS_05429
Name SwissTargetPrediction
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline David Gfeller

Publications for SwissTargetPrediction

SwissTargetPrediction citations


A Computational Approach Using Bioinformatics to Screening Drug Targets for Leishmania infantum Species

PMCID: 5896251
PMID: 29785196
DOI: 10.1155/2018/6813467

[…] avonoid was evaluated by applying distinct algorithms, which used chemical similarity to identify proteins with known ligands to show similarity to this molecule []. In the results, the TargetHunter, SwissTargetPrediction, SEA, and PASS servers identified 21, 15, 75, and 630 putative targets, respectively. A positive consensual result was obtained with three hits: NADPH oxidase, Aldose reductase, […]


A census of P. longum’s phytochemicals and their network pharmacological evaluation for identifying novel drug like molecules against various diseases, with a special focus on neurological disorders

PLoS One
PMCID: 5761900
PMID: 29320554
DOI: 10.1371/journal.pone.0191006

[…] taset was filtered to remove duplicate entries. Human proteins targeted by the phytochemicals were predicted from STITCH 5.0 (Search Tool for Interactions of Chemicals and proteins) [], BindingDB [], SwissTargetPrediction [] and PCIDB.The protein-chemical interaction reported in STITCH comes from the manually curated datasets including DrugBank [] GLIDA [], Matador [], TTD (Therapeutic target data […]


PTS: a pharmaceutical target seeker

PMCID: 5750839
DOI: 10.1093/database/bax095

[…] proaches use molecular docking techniques, while PTS does not employ ligand-receptor docking techniques and can still produce results where the receptor structure data are not available. Both PTS and SwissTargetPrediction are web-based target fishing tools. The four testing cases were tested on both tools, which produced similar results. Additionally, small scale of structurally diverse drugs that […]


Crystal structure, Hirshfeld analysis and mol­ecular docking with the vascular endothelial growth factor receptor 2 of (3Z) 5 fluoro 3 (hy­droxy­imino)­indolin 2 one

PMCID: 5499275
PMID: 28775867
DOI: 10.1107/S2056989017008301

[…] mal = 0.90997, HOMO = −9.265 eV, LUMO = −1.337 eV and energy gap = 7.928 eV (Macrae et al., 2008; Stewart, 2013, 2016). The biological target prediction for the title compound was calculated with the SwissTargetPrediction webserver based on the bioisosteric similarity to the isatin entity (Gfeller et al., 2013, 2014). As result of this screening, the title compound showed a promising theoretical s […]


Bioinformatics and Drug Discovery

Curr Top Med Chem
PMCID: 5421137
PMID: 27848897
DOI: 10.2174/1568026617666161116143440

[…] teraction, it is natural to infer that other proteins with similar sequence or structure may also bind to the ligand. Such similarity-based approach [, ] is the conceptual foundation for the software SwissTargetPrediction [].It is important to keep in mind that a structure determined by X-ray crystallography or by NMR represents only a snapshot of structural dynamics, and that protein structure ca […]


Drug repositioning for enzyme modulator based on human metabolite likeness

BMC Bioinformatics
PMCID: 5471945
PMID: 28617219
DOI: 10.1186/s12859-017-1637-5

[…] tabolites is a gold standard positive set because they all resemble innate metabolites by definition. Then, we compared the performance of our method to known drug-target prediction methods including SwissTargetPrediction [], TargetNet [], and Libdock algorithm of molecular docking []. After showing that our method outperforms the other drug-target prediction methods in terms of drug-enzyme relati […]

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SwissTargetPrediction institution(s)
Swiss Institute of Bioinformatics (SIB), Quartier Sorge, Bâtiment Génopode, Lausanne, Switzerland

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