SyGMa statistics

Tool stats & trends

Looking to identify usage trends or leading experts?

SyGMa specifications

Information


Unique identifier OMICS_15732
Name SyGMa
Alternative name Systematic Generation of potential Metabolites
Software type Package/Module
Interface Command line interface
Restrictions to use Academic or non-commercial use
Operating system Unix/Linux
Programming languages Python
License GNU General Public License version 3.0
Computer skills Advanced
Stability Stable
Requirements
RDKit
Maintained Yes

Download


download.png

Versioning


No version available

Documentation


Maintainer


  • person_outline Lars Ridder

Publication for Systematic Generation of potential Metabolites

SyGMa citations

 (10)
library_books

Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma

2017
PMCID: 5647477
PMID: 29071080
DOI: 10.1136/bmjresp-2017-000217

[…] therapy alone, indicating better control of airway inflammation. Based on this evidence, two double-blind regulatory RCTs of as-needed budesonide/formoterol (SYmbicort Given as needed in Mild Asthma, SYGMA) are currently underway, together with an open-label RCT of as-needed budesonide/formoterol in patients currently taking only SABA reliever therapy (Novel Symbicort Therapy As Reliever Therapy, […]

library_books

RD Metabolizer: an integrated and reaction types extensive approach to predict metabolic sites and metabolites of drug like molecules

2017
Chem Cent J
PMCID: 5515729
PMID: 29086838
DOI: 10.1186/s13065-017-0290-4

[…] approaches. Expert systems mainly employ generic metabolic rules derived by expert to predict structures of metabolites. Typical examples of expert systems are META [–], MetabolExpert [], Meteor [], SyGMa [], TIMES []. For the fingerprint-based data mining approaches, MetaPrint2D-React [], an extension of MetaPrint2D, is a typical and representative method. It is and allows users to predict struc […]

library_books

Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing

2017
Sci Rep
PMCID: 5468315
PMID: 28607474
DOI: 10.1038/s41598-017-03171-4

[…] ots. She has received consulting/lecture fees or served as a board member for Alertness Solution, Ceridian, Davis Joint Unified School Board, San Jose State University Foundation, Pugot Sound Pilots, Sygma and Torvec. RWP is a co-founder of and shareholder in Empatica Inc and Affectiva Inc and serves on the board of Empatica. She is inventor or co-inventor on over two dozen patents, mostly in the […]

library_books

Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher dose budesonide as step up from low dose inhaled corticosteroid treatment

2017
PMCID: 5397768
PMID: 28427362
DOI: 10.1186/s12890-017-0401-y

[…] trials are required to confirm these findings in patients with milder asthma and lower baseline reliever use. The use of ICS/LABA as-needed in mild asthma is currently being evaluated in the ongoing SYGMA studies []. In the present analysis, the selection only of patients on Step 2 treatment at entry, and sub-division by baseline as-needed reliever use, reduced the power of the analyses, with onl […]

library_books

The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given ‘as needed’ in mild asthma: study protocols for two randomised controlled trials

2017
PMCID: 5223341
PMID: 28069068
DOI: 10.1186/s13063-016-1731-4

[…] The primary outcome measure in SYGMA1, well-controlled asthma weeks (as-needed budesonide/formoterol versus as-needed terbutaline (superiority) and as-needed budesonide/formoterol versus maintenance budesonide plus as-needed terbut […]

library_books

TRPA5, an Ankyrin Subfamily Insect TRP Channel, is Expressed in Antennae of Cydia pomonella (Lepidoptera: Tortricidae) in Multiple Splice Variants

2016
PMCID: 5026476
PMID: 27638948
DOI: 10.1093/jisesa/iew072

[…] h). Amplifications were conducted according to the recommended protocols. Primers were designed by hand using existing contig data as reference. Thermodynamic features were checked by OligoEvaluator (Sygma Genosys, http://www.oligoevaluator.com), and putative oligodimerization was checked by OligoAnalyzer 3.1 (Integrated DNA Technologies, http://eu.idtdna.com/calc/analyzer). Primer melting tempera […]

Citations

Looking to check out a full list of citations?

SyGMa institution(s)
Molecular Design and Informatics, Organon, part of Schering-Plough Corporation, Oss, Netherlands

SyGMa reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review SyGMa