Allows efficient searches for candidate genes in a genomic locus. S2G uses known genes whose defects cause phenotypically similar syndromes. It can be used to identify molecules that interact with or are related to a gene of choice. The tool finds candidate genes for a human syndrome based on known genes for similar syndromes. It is composed of two parts: a phenotype Online Mendelian Inheritance in Man (OMIM)-based search engine and a gene prioritizing engine.
The Morris Kahn Laboratory of Human Genetics, National Institute for Biotechnology in the Negev, Ben Gurion University, Beer-Sheva, Israel; The Genetics Institute, Soroka Medical Center, Ben Gurion University, Beer-Sheva, Israel
Syndrome to Gene funding source(s)
Supported by the Morris Kahn Family Foundation for Humanitarian Support.