Synergizer statistics

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Associated diseases

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Synergizer specifications

Information


Unique identifier OMICS_18326
Name Synergizer
Interface Web user interface, Application programming interface
Restrictions to use None
Input data IDs to translate.
Output data A two-column table showing the desired translations.
Programming languages Java, Javascript, Perl, PHP, Python, Ruby
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Frederick Roth <>

Publication for Synergizer

Synergizer in publications

 (17)
PMCID: 5478098
PMID: 28632788
DOI: 10.1371/journal.pbio.2001644

[…] molecules that did not elicit a phenotype from any mutant in any response pattern gene. we performed checkerboard assays, a standard measure of synergistic interactions [], for each predicted synergizer or negative control combined with trimethoprim or sulfamethizole. all small molecules and their minimum inhibitory concentrations (mics) are listed in ., all values are against e. coli […]

PMCID: 4996253
PMID: 27579293
DOI: 10.2147/OV.S66217

[…] tumor cells to prevent the suppression of viral replication. during ov therapy, a chemotherapeutic agent could be administered to deplete suppressive treg populations, together with a viral synergizer to solidify ifn suppression. post-ov therapy, compounds capable of promoting immune memory formation may be administered to solidify tumor control and protect against relapse., in vitro […]

PMCID: 4664750
PMID: 26697374
DOI: 10.1016/j.gdata.2015.09.015

[…] all transcript and gene ids were mapped to corresponding ensemble gene ids. for ensemble transcript ids, corresponding ensemble gene ids were obtained using the biomart community portal . the synergizer web application was used to convert gene ids from other annotation frameworks to ensemble gene ids. the resulting table (supplementary table 2) was then merged with the table of probeset […]

PMCID: 4558850
PMID: 26163674
DOI: 10.1093/gbe/evv132

[…] s1 and s2, supplementary material online. proteins were quantified in summed ion intensity, and the resulting proteomic data set was normalized using the same method as the genomic data., the synergizer (http://llama.mshri.on.ca/synergizer/translate/, last accessed july 22, 2015) was used to match proteins back to their parent transcripts by searching the ensembl database. this produced […]

PMCID: 4370562
PMID: 25799455
DOI: 10.1371/journal.pone.0120280

[…] a biocompatible, non-aqueous (na) delivery vehicle may also have membrane-disrupting effects against bacterial pathogens and therefore, may be a clinically useful solubilizing agent and accelerant (synergizer) with gml []. in addition to its activity as a general microbial disruptant, the na vehicle increases gml solubility by over 100-fold, allowing higher doses of gml to be delivered […]


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Synergizer institution(s)
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA; Center for Cancer Systems Biology, Dana-Faber Cancer Institute, Boston, MA, USA
Synergizer funding source(s)
Supported by National Institutes of Health. (grants HG003224, HG0017115, and HL081341), Keck Foundation.

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