Provides a list of verified ciliary genes, which can be used as a reference dataset of cilia genes. SCGS facilitates determination of objective cut-off thresholds via receiver operator characteristic (ROC) curves. It was constructed by collecting 27 ciliary studies from Cildb, which holds a large collection of ciliary datasets. The database can be used to train and evaluate bioinformatics tools, and can be considered as a reference resource.
Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre, Nijmegen, The Netherlands; Section of Ophthalmology and Neuroscience, Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James’s University Hospital, Leeds, UK; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands
SCGS funding source(s)
Supported by the European Community's Seventh Framework Programme FP7/2009, grant agreement number 241955, SYSCILIA.