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SYSNPs specifications


Unique identifier OMICS_23295
Alternative name Select Your SNPs
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained No


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Additional information

Publication for Select Your SNPs

SYSNPs citations


NF kB2 Genetic Variations are Significantly Associated with Non Small Cell Lung Cancer Risk and Overall Survival

Sci Rep
PMCID: 5869671
PMID: 29588475
DOI: 10.1038/s41598-018-23324-3
call_split See protocol

[…] be correlated with overall survival (OS) of patients with multiple myeloma. In addition, tagging SNPs rs7897947 and rs11574852 were selected through the use of the internet-based tools “Tagger” and “SySNPs for the CEU population,. The cut-off for minor allele frequency was determined at 5% and the coefficient of determination r2 = 0.8 was captured. Genomic location, minor allele frequencies (MAF) […]


Are IL18RAP gene polymorphisms associated with body mass regulation? A cross sectional study

BMJ Open
PMCID: 5695454
PMID: 29146643
DOI: 10.1136/bmjopen-2017-017875
call_split See protocol

[…] ntified and diluted to a final concentration of 100 ng ⁄µL. The IL18RAP single nuclear polymorphisms (SNPs) were selected for genotyping based on the conjunction of several parameters selected in the SYSNPs web tool: heterozygosity in a Caucasian population (>10% for the minor allele frequency), position and spacing along the gene and a possible functional effect ( […]


A gene environment interaction analysis of plasma selenium with prevalent and incident diabetes: The Hortega study

Redox Biol
PMCID: 5403796
PMID: 28437656
DOI: 10.1016/j.redox.2017.04.022

[…] (Chemagen), and quantified it with PicoGreen dsDNA Quantification Reagent (Invitrogen, Carlsbad, CA, USA). DNA was diluted to a final concentration of 100 ng/µl. We used bibliography searches and the SYSNPS program , based on public data sources including Ensembl and HapMap (GRCh36), to identify 597 single nucleotide polymorphisms (SNPs) from 155 candidate genes implicated in diabetes metabolic pa […]


Pharmacogenomic study in patients with multiple sclerosis

PMCID: 4582905
PMID: 26445728
DOI: 10.1212/NXI.0000000000000154

[…] for GABA and glutamate receptors were selected through bibliographical searches, and a total of 384 biologically informative single nucleotide polymorphisms (SNPs) were selected for genotyping using Select Your SNPs, an online tool for selecting tagSNPs from a roster of candidate genes. […]


The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study

J Transl Med
PMCID: 4557824
PMID: 26329592
DOI: 10.1186/s12967-015-0652-4

[…] related SNPs from six genes were selected based on their minor allele frequency (MAF) in Caucasians (0.1 or more), location, distribution, tag-SNP characteristics using the SySNP program (‎), and their possible effects on function as determined in previous studies by our group []. The selected genes and reference names, chromosome position, locus, and the MAF of the selected […]


Polymorphisms in Endothelin System Genes, Arsenic Levels and Obesity Risk

PLoS One
PMCID: 4370725
PMID: 25799405
DOI: 10.1371/journal.pone.0118471
call_split See protocol

[…] m (Chemagen, Baesweiler, Germany). DNA was quantified and diluted to a final concentration of 100 ng ⁄μL.EDN system SNPs for genotyping were selected based on the conjunction of several parameters by SYSNPs []: heterozygosity (>10% for the minor allele frequency) in a Caucasian population, position and spacing along the gene, and possible functional effect ( Eigh […]


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SYSNPs institution(s)
Institut de Biologia Evolutiva (UPF-CSIC), Barcelona Biomedical Research Park (PRBB), Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Spain; Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain; Spanish National Institute for Bioinformatics (INB), Spain; Bioinformatics Unit (UBio), Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; Institut Municipal d’Investigació Mèdica (IMIM), Barcelona, Spain; CIBER en Enfermedades Raras (CIBERER), Spain
SYSNPs funding source(s)
Partially supported by Red Temática de Investigación Cooperativa en Cáncer, Fundació La Marató de TV3, CIBER en Epidemiología y Salud Pública (Ciberesp), CIBER en Enfermedades Raras (Ciberer) and the National Institute for Bioinformatics, a Platform of Genoma España.

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