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SYSTERS specifications


Unique identifier OMICS_03877
Restrictions to use None
Maintained Yes


  • person_outline Eike Staub

Publication for SYSTERS

SYSTERS citations


Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum

PLoS One
PMCID: 4403809
PMID: 25894582
DOI: 10.1371/journal.pone.0124177

[…] t of the protein. Furthermore, Pfam database was used to predict the function of proteins based on sequence similarity. We have also performed protein classification using clustering techniques using SYSTERS and ProtoNet. SYSTERS is a database of protein family which uses BLASTp to search the database for similar sequences and provides the cluster of proteins formed on the basis of functional simi […]


Topological analysis of the Escherichia coli WcaJ protein reveals a new conserved configuration for the polyisoprenyl phosphate hexose 1 phosphate transferase family

Sci Rep
PMCID: 4361858
PMID: 25776537
DOI: 10.1038/srep09178

[…] Amino acid sequences of PHPT proteins were downloaded from the SYSTERS database (Cluster O 141559; All these proteins contain PFAM PF02397 corresponding to bacteria […]


Expression and Mutational Analysis of DinB Like Protein DR0053 in Deinococcus radiodurans

PLoS One
PMCID: 4338110
PMID: 25706748
DOI: 10.1371/journal.pone.0118275

[…] terminants of the DR0053 protein, a bioinformatic analysis was performed. The pfam domain search demonstrated that DR0053 belongs to the DinB protein family (pfam05163). This family consists of seven SYSTERS (SYSTEmatic Re-Searching) protein families []. Among them, DR0053 belongs to the family of cluster O154983 with six other proteins (). The relationship between DR0053 and the other proteins in […]


Structure based function analysis of putative conserved proteins with isomerase activity from Haemophilus influenzae

3 Biotech
PMCID: 4569619
PMID: 28324524
DOI: 10.1007/s13205-014-0274-1

[…] function prediction of HPs [47]. The databases such as Pfam (Punta et al. ), PANTHER (Mi et al. ), SMART (Letunic et al. ), SUPERFAMILY (Gough et al. ), CATH (Sillitoe et al. ), CDART (Geer et al. ), SYSTERS (Meinel et al. ), ProtoNet (Rappoport et al. ) and SVMProt (Cai et al. ) were used for precise domain annotation in HPs. Similarly, instead of direct sequence similarity, we also used domain a […]


Structure based functional annotation of putative conserved proteins having lyase activity from Haemophilus influenzae

3 Biotech
PMCID: 4434415
PMID: 28324295
DOI: 10.1007/s13205-014-0231-z

[…] 4717 suggest that P44717 is comprised of two domains, CorC/HlyC and CBS domain. By applying the clustering algorithms, we analyzed that HP P44717 is a member of cluster 143846 (CBS domain protein) of SYSTERS (Meinel et al. ) and cluster 4144744 (Transporter-associated region) of ProtoNet (Rappoport et al. ), and a member of transmembrane family protein. Sequence-based motifs are discovered using I […]


Functional Annotation of Conserved Hypothetical Proteins from Haemophilus influenzae Rd KW20

PLoS One
PMCID: 3877243
PMID: 24391926
DOI: 10.1371/journal.pone.0084263

[…] nments to all 429 HPs from H. influenzae are described in . The functional domain of a protein is predicted by using various publically available databases such as Pfam, SUPERFAMILY , CATH, PANTHER , SYSTERS , SVMProt , CDART , SMART , and ProtoNet (). The database SYSTERS was used for clustering proteins on the basis of their functions. We used BLASTp for searching SYSTERS database and the outpu […]

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SYSTERS institution(s)
Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, Berlin, Germany

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