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TCC | An R package for comparing tag count data with robust normalization strategies

Allows users to perform differential expression (DE) analysis of tag count data. The Tag Count Comparison purpose is to reduce potential differentially expressed genes (DEGs) before performing the data normalization. It provides tools to perform multi-step normalization methods based on DEG elimination strategy (DEGES). This tool supplies a simple unified interface to perform such analyses with combinations of functions provided by edgeR, DESeq, and baySeq.

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TCC classification

TCC specifications

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Tag Count Comparison
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
GNU General Public License version 2.0

TCC distribution


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TCC support



  • Koji Kadota <>


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Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Advanced Science Research Center, Kanazawa University, Kanazawa, Japan

Funding source(s)

Supported by grants (KAKENHI 24500359 and 22128008) from the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT).

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