TALOS+ statistics

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Citations per year

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Popular tool citations

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Tool usage distribution map

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Associated diseases

Associated diseases

TALOS+ specifications


Unique identifier OMICS_03404
Alternative name Torsion Angle Likeliness Obtained from Shift and Sequence Similarity
Interface Web user interface
Restrictions to use None
Output data The predictions for individual residues with missing chemical shifts, and the secondary structure.
Computer skills Basic
Stability Stable
Registration required Yes
Maintained Yes


  • person_outline Yang Shen <>
  • person_outline Ad Bax <>

Additional information

https://spin.niddk.nih.gov/NMRPipe/talos/ TALOS+ is now also installed as part of the NMRPipe System.

Publications for Torsion Angle Likeliness Obtained from Shift and Sequence Similarity

TALOS+ in publication

PMCID: 4481645
PMID: 26112753
DOI: 10.1038/srep11502

[…] patterns are indicative of ~6 α-helices, our structural refinement () using 1h-1h noe-based distance restraints with >20 noe contacts per residue over most of the globular region (), coupled with talos+32 dihedral angle restraints () and hydrogen-deuterium exchange-derived hydrogen bond restraints (), demonstrates 5 α-helical regions. despite the lack of a continuous helix in the putative […]

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TALOS+ institution(s)
Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
TALOS+ funding source(s)
Supported by the Intramural Research Program of the NIDDK, NIH.

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