TANTIGEN specifications


Unique identifier OMICS_11286
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Version 1.0
Maintained Yes


  • person_outline Guanglan Zhang
  • person_outline Vladimir Brusic

Publication for TANTIGEN

TANTIGEN citations


Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

Genome Biol
PMCID: 4377852
PMID: 25853550
DOI: 10.1186/s13059-015-0620-6

[…] ], Dana Farber repository [], and CIG-DB []. Automatized HTTP-mediated download and HTML processing retrieved all records from the following databases: MHCBN [], PeptideDatabase [], SYFPEITHI [], and TANTIGEN []. The entries were filtered to select for HLA class I-binding epitopes. The total number of reported peptide-MHC affinities (55,000) was five times smaller than the predicted CRC antigenome […]


Big Data Analytics in Immunology: A Knowledge Based Approach

Biomed Res Int
PMCID: 4090507
PMID: 25045677
DOI: 10.1155/2014/437987

[…] ficient antigenicity analysis, in every knowledgebase and within each antigen entry, we embedded a tool that performs on-the-fly binding prediction to 15 frequent HLA class I and class II alleles. In TANTIGEN, an interactive visualization tool, mutation map, has been implemented to provide a global view of all mutations reported in a tumor antigen. shows a screenshot of mutation map of tumor anti […]

TANTIGEN institution(s)
Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA; School of Medicine and Bioinformatics Center, Nazarbayev University, Astana, Kazakhstan; Department of Computer Science, Metropolitan College, Boston University, Boston, MA, USA
TANTIGEN funding source(s)
Supported by The Danish Council for Independent Research Grant 4184-00211B), NIH Grant UO1 AI090043 and SU2C-AACR-DT13-14 and Dana-Farber Cancer Institute, Cancer Vaccine Center Funds.

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