TAPPA specifications


Unique identifier OMICS_19190
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Java
Computer skills Advanced
Stability No
Maintained No


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Publication for TAPPA

TAPPA citations


Advanced Applications of RNA Sequencing and Challenges

Bioinform Biol Insights
PMCID: 4648566
PMID: 26609224
DOI: 10.4137/BBI.S28991

[…] ns and the interactions of the genes in the pathway are considered. Accordingly, interacting differentially expressed gene pairs are preferentially weighted over two non-interacting genes. Similarly, TAPPA is a scoring method in which higher weights are automatically assigned to hub genes and interacting gene pairs. DEAP identifies the most differentially expressed path to provide a refined focus […]


Identification of highly synchronized subnetworks from gene expression data

BMC Bioinformatics
PMCID: 3698028
PMID: 23901792
DOI: 10.1186/1471-2105-14-S9-S5

[…] e levels of all genes in the network (hereafter referred to as the Additive scoring method): (7) z A d d i t i v e = ∑ i ∈ A z i (2) A metric that we previously proposed in our TAPPA software package [] (hereafter referred to as the TAPPA scoring method) that only utilize the topological characteristics of the PPI network: (8) z T o p o = ∑ i ∈ A ∑ j ∈ A […]

TAPPA institution(s)
The Max McGee National Research Center for Juvenile Diabetes & The Human and Molecular Genetics Center, The Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI, USA
TAPPA funding source(s)
Supported by the National Institute of Diabetes and Digestive and Kidney Diseases under grant No. R01DK080100.

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