TargetHunter specifications

Information


Unique identifier OMICS_04909
Name TargetHunter
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for TargetHunter

TargetHunter in publications

 (6)
PMCID: 5896251
PMID: 29785196
DOI: 10.1155/2018/6813467

[…] in which similar molecules are likely to have equivalent properties []. for this, the chemical structure of strychnobiflavone was retrieved from the pubchem database [] and uploaded to the targethunter [], swisstargetprediction [], similarity ensemble approach (sea) [], and pass online [] servers. threshold values were selected by default parameters, and molecular targets […]

PMCID: 5039409
PMID: 27678063
DOI: 10.1038/srep33963

[…] we investigated sini decoction, a well-known tcm consisting of three herbs, as a model. we applied our established diseases-specific chemogenomics databases and our systems pharmacology approach targethunter to explore synergistic mechanisms of sini decoction in the treatment of cardiovascular diseases. (1) we constructed a cardiovascular diseases-specific chemogenomics database, including […]

PMCID: 4858665
PMID: 27150638
DOI: 10.1038/srep25491

[…] tryptanthrin (), they could also inhibit cell viability and induce apoptosis on k562 cells in a dose-dependent manner., in this study, pharmmapper server (http://lilab.ecust.edu.cn/pharmmapper/) and targethunter (http://www.cbligand.org/targethunter/) tools were selected for potential drug target identification. pharmmapper server is a spatial arrangement of features essential for a molecule […]

PMCID: 4842778
PMID: 27199640
DOI: 10.3389/fnins.2016.00177

[…] domain-specific chemogenomics database allowing the identification of off-target effects and the repurposing of compounds (liu et al., ). alzplatform contains the established computational algorithm targethunter, which is an in silico target identification tool for small molecules (wang et al., )., while there is a wealth of open access chemical information available to aid repurposing of fda […]

PMCID: 4261112
PMID: 25512684
DOI: 10.6026/97320630010684

[…] tarfisdock [], pharmmapper [], reversescreen3d [], idtarget [], target hunter [] and chemmapper []., in the current study, a unified approach integrating pharmmapper, reversescreen3d and targethunter to identify the potential targets for n.sativa bioactive ingredients. the targets prioritized were further validated for its anti-cancerous activity by matching up to experimental […]


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TargetHunter institution(s)
Department of Pharmaceutical Sciences, School of Pharmacy, Computational Chemical Genomics Screening Center, Pittsburgh, PA, USA

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