An integrated data warehouse based on the versatile InterMine framework, which models biological entities (such as genes and proteins) as ‘objects’ and their relationships as ‘references’ to other objects. TargetMine was optimized for target discovery and prioritization of candidate genes and was successfully employed for gene prioritization in various studies. We have developed an auxiliary toolkit to assist TargetMine users to visualize and analyse the diverse biological datatypes seamlessly. The enhanced system enables the users to perform complicated queries, select and define query parameters and engage multiple datasets simultaneously, thereby providing a wide range of possibilities for the users to interrogate the biological data space that may not be easily achieved using other tools. It also allows the users to export publication quality images and the results in a variety of formats such as Excel sheets.
National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, Japan
TargetMine funding source(s)
This work was in part supported by Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (25430186 and 25293079) and from Japan Agency for Medical Research and Development (The adjuvant database project).