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|Interface||Web user interface|
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- Homo sapiens
- person_outline Ben Lewis
Publication for TargetScanS
Tools for Sequence Based miRNA Target Prediction: What to Choose?
[…] lgorithm used to predict miRNA targets in vertebrates . Since then, this tool has been improved through new versions and additional algorithms that have helped to improve match prediction accuracy: TargetScanS , TargetScan PCT , TargetScan context+ score [,,]. All of these are described below. These web-based tools have two search options: the gene symbol and/or the species-specific miRNA na […]
MicroRNA: Biological and Computational Perspective
[…] r target predictions in Arabidopsis. In the past few years progress has also been made in the prediction of targets in other species , , , , , , , , , , , .Commonly used programs are TargetScan and TargetScanS , miRanda , , DIANA-microT , RNAhybrid , PicTar , and others.Although the programs differ in technical details, many of the programs use basically the same principles in their target findi […]
Identifying microRNA targets in different gene regions
[…] e pSILAC method  and evaluated how our target predictions correlate with the results in the pSILAC dataset. To achieve a comparable predicted number of targets with other well-known methods such as TargetScanS and PicTar, we set the cut-off values ΔGduplexcutoff=-15.0 kcal/mol and ΔΔGcutoff=-10.0kcal/mol, respectively.Figure shows the ratio of the fraction of predicted miRNA targets for which p […]
A Positive Feedback Mechanism That Regulates Expression of miR 9 during Neurogenesis
[…] th Mef2C.Since we predict that Mef2C and miR-9 are coordinately involved in neurogenesis and HDAC4 opposes this mechanism, we searched for potential feedback networks between Mef2C and miR-9. We used TargetScanS , to determine if any of these mRNAs were potential targets of miR-9. The 3′UTR of HDAC4 contained four predicted miR-9 response elements (RE) including one closest to the coding sequence […]
Functional divergence of the rapidly evolving miR 513 subfamily in primates
[…] otung (http://www.cs.cmu.edu/~durand/Notung/). The species tree was based on the NCBI taxonomy tree (http://www.ncbi.nlm.nih.gov/taxonomy). To identify potential targets of miR-513 sequences, we used TargetScanS , and eight genes with top rank values were selected for functional testing. […]
Target Gene and Function Prediction of Differentially Expressed MicroRNAs in Lactating Mammary Glands of Dairy Goats
[…] e database, miRGen v3  is an integrated database that includes the prediction results of six algorithms, DIANA-microT, miRanda (microran.org), miRanda (miRBase), PicTar (4-way), PicTar (5-way), and TargetScanS. In miRGen, all PicTar targets were downloaded as UCSC Tracks from the UCSC Genome Browser Database. “4-way” refers to a 4-species conservation constraint (human/mouse/rat/dog), and “5-way […]
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