TASER protocols

TASER computational protocol

TASER specifications


Unique identifier OMICS_24397
Alternative name Test of Association using SEquencing Reads
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data A specification file, a control file, a region file, and an optional annotation.
Output data A file including information of the gene name, the number of loci in the gene after restricting to the annotated regions/sites, the number of loci that were screened in, the number of loci that were screened in and passed the threshold, the estimated number of SNVs, the p-value of the New-SB test, and the p-value of the New-STB test.
Operating system Unix/Linux
Programming languages C, C++
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes



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  • person_outline Yi-Juan Hu <>

Publication for Test of Association using SEquencing Reads

TASER IN pipeline

PMCID: 5455050
PMID: 28524840
DOI: 10.4103/0366-6999.206348

[…] was detected in this patient. this mutation was not found in the patient's parents and 100 unrelated healthy individuals. functional assessment of this mutation was assessed using mutation taser (http://www.mutationtaster.org/). the mutation was predicted to cause the 96th amino acid of the gata3, tryptophan, to be substituted by glycine, resulting in a frameshift (p.w96gfs*99) […]

TASER institution(s)
Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA; Centers for Disease Control and Prevention, Atlanta, GA, USA
TASER funding source(s)
Supported by National Institutes of Health grant R01GM116065-01A1 and Emory’s University Research Committee grant.

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