TASER specifications


Unique identifier OMICS_24397
Alternative name Test of Association using SEquencing Reads
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data A specification file, a control file, a region file, and an optional annotation.
Output data A file including information of the gene name, the number of loci in the gene after restricting to the annotated regions/sites, the number of loci that were screened in, the number of loci that were screened in and passed the threshold, the estimated number of SNVs, the p-value of the New-SB test, and the p-value of the New-STB test.
Operating system Unix/Linux
Programming languages C, C++
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes




No version available


  • person_outline Yi-Juan Hu

Publication for Test of Association using SEquencing Reads

TASER citation


Genome wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

Sci Rep
PMCID: 5668427
PMID: 29097723
DOI: 10.1038/s41598-017-15062-9

[…] to inflated type I errors, but discarding those samples with insufficient read depth can result in a loss of power (or, in this case, the loss of all controls). We therefore used the software package TASER, which effectively re-calls variants in both cases and controls, allowing for systematic differences in read depth (and other factors), at the same time as constructing a test statistic.In an ad […]

TASER institution(s)
Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA; Centers for Disease Control and Prevention, Atlanta, GA, USA
TASER funding source(s)
Supported by National Institutes of Health grant R01GM116065-01A1 and Emory’s University Research Committee grant.

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