A freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness.
Department of Molecular Biology, University of California, San Diego, CA, USA; Department of Medical Sciences, Boston University School of Medicine, Boston, MA, USA; Department of Biological Engineering, School of Life Sciences, Beijing Institute of Technology, Beijing, China; Department of Biology, Wilfrid Laurier University, Waterloo, ON, Canada