TCGA SpliceSeq specifications

Information


Unique identifier OMICS_30506
Name TCGA SpliceSeq
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Version 2
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Michael Ryan

Additional information


http://bioinformatics.mdanderson.org/TCGASpliceSeq/faq.jsp

Publication for TCGA SpliceSeq

TCGA SpliceSeq citations

 (2)
library_books

Loss of TDP43 inhibits progression of triple negative breast cancer in coordination with SRSF3

2018
Proc Natl Acad Sci U S A
PMCID: 5899436
PMID: 29581274
DOI: 10.1073/pnas.1714573115

[…] To investigate AS patterns among various breast cancer subtypes, we downloaded percent spliced in (PSI) values for breast cancer splice events from The Cancer Genome Atlas (TCGA) SpliceSeq, a web-based resource (). A total of 45,421 splice events from 10,480 expressed genes were acquired from 1,094 available samples representing four breast cancer subtypes (luminal A, lu […]

library_books

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T PLL

2018
Nat Commun
PMCID: 5814445
PMID: 29449575
DOI: 10.1038/s41467-017-02688-6

[…] exons in 85 genes overlapped with events reported for acute myeloid leukemia (AML) and 105 exons in 67 genes overlapped with events reported for diffuse large B-cell lymphoma (DLBCL) according to the TCGA SpliceSeq data base. Alternative splicing events in 56 genes are overlapping between all 3 hematologic malignancies (T-PLL, AML, and DLBCL). […]

TCGA SpliceSeq institution(s)
Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; In Silico Solutions, Falls Church, VA, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
TCGA SpliceSeq funding source(s)
Supported by U.S. National Cancer Institute (NCI; MD Anderson TCGA Genome Data Analysis Center) [CA143883, CA083639]; Cancer Prevention Research Institute of Texas (CPRIT) [RP130397]; Mary K. Chapman Foundation, the Michael & Susan Dell Foundation (honoring Lorraine Dell); and the MD Anderson Cancer Center Support Grant P30 CA016672 (the Bioinformatics Shared Resource).

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