Identifies variable (V) and joining (J) segments, as well as CDR3 region sequences using K-string-based algorithm for translated nucleotide queries. Specifically designed to handle short reads, the tool correctly accounts for sequencing reads with missing CDR3 region in order to provide an unbiased V/J segment usage data.

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TCRklass classification

TCRklass specifications

Software type:
Package
Restrictions to use:
None
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Stability:
Stable
Interface:
Command line interface
Biological technology:
Illumina
Programming languages:
C++, Perl
Computer skills:
Advanced

Credits

Publications

  • (Yang et al., 2014) TCRklass: A New K-String-Based Algorithm for Human and Mouse TCR Repertoire Characterization. Journal of immunology.
    PMID: 25404364

Link to literature

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