A database that currently documents 1338 relationships between 497 tea bioactive compounds and 206 diseases (or phenotypes) manually culled from over 300 published articles. TBC2health contains comprehensive information about a bioactive relationship that can be accessed in three aspects: (i) compound information, (ii) disease (or phenotype) information and (iii) evidence and reference. Using the curated bioactive relationships, a bipartite network was reconstructed and the corresponding network (or sub-network) visualization and topological analyses are provided for users.
School of Tea and Food Technology, Anhui Agricultural University, Hefei, China; School of Agronomy, Anhui Agricultural University, Hefei, China; Department of Food Science, Rutgers University, NB, NJ, USA; College of Information and Computer science, Anhui Agricultural University, Hefei, China; State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, China
TBC2health funding source(s)
This work was supported by National Key Basic Research Program of China (grant no. 2012CB722903); Collaborative Innovation Center of Agri-forestry Industry in Dabieshan Area; Earmarked Fund for Modern Agro-industry Technology Research System in Tea Industry (grant no. CARS-23); National Natural Science Foundation of China (grant nos. 31301248 and 31201335); China Postdoctoral Science Foundation (grant nos. 2013M531498 and 2012M511397).