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Telomere content estimation software tools | Whole-genome sequencing analysis

Telomere shortening plays an important role in cellular aging and tumor suppression. The availability of large next-generation sequencing cohorts of matched tumor and control samples enables a computational high-throughput analysis of changes in…
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TelSeq
Desktop

TelSeq

A method to measure average telomere length from whole genome or exome shotgun…

A method to measure average telomere length from whole genome or exome shotgun sequence data. TelSeq allows any cohort with existing genome-wide sequence data, including increasingly many cancer…

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Computel
Desktop

Computel

An alternative, alignment-based approach for telomere length estimation using…

An alternative, alignment-based approach for telomere length estimation using whole-genome NGS data. We have performed its extensive validation using both synthetic and experimental data. Comparison…

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Telomerecat
Desktop

Telomerecat Telomere Computational Analysis Tool

Estimates telomere length from cancer whole genome sequencing (WGS) data.…

Estimates telomere length from cancer whole genome sequencing (WGS) data. Telomerecat calculates and corrects the number of Interstitial telomeric repeat (ITR)-originating reads without consideration…

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TelomereHunter
Desktop

TelomereHunter

A tool for estimating telomere content from human whole-genome sequencing data.…

A tool for estimating telomere content from human whole-genome sequencing data. TelomereHunter is designed to take BAM files from a tumor and a matching control sample as input. However, it is also…

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