TEPIC specifications

Information


Unique identifier OMICS_15433
Name TEPIC
Software type Framework/Library
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C++, Python, R, Shell (Bash)
License MIT License
Computer skills Advanced
Version 2.1
Stability Stable
Requirements
Bedtools, g++ complier
Maintained Yes

Download


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Versioning


No version available

Maintainer


  • person_outline Marcel Schulz

Publications for TEPIC

TEPIC citation

library_books

Probing instructions for expression regulation in gene nucleotide compositions

2018
PLoS Comput Biol
PMCID: 5766238
PMID: 29293496
DOI: 10.1371/journal.pcbi.1005921

[…] the opening of the chromatin) in the promoter region of each gene, which explains their good accuracy on randomized or maximized variables.We indeed observed a similar bias in the results obtained by TEPIC [], a regression method that predicts gene expression from PWM scores and open-chromatin data. Specifically, TEPIC computes a TF-affinity score for each gene and each PWM by summing up the TF af […]

TEPIC institution(s)
Cluster of Excellence on Multimodal Computing and Interaction, Saarland Informatics Campus, Saarbrücken, Germany; Max Planck Institute for Informatics, Saarland Informatics Campus, Saarbrücken, Germany; Graduate School of Computer Science, Saarland Informatics Campus, Saarbrücken, Germany; Chair for Clinical Bioinformatics, Saarland Informatics Campus, Saarbrücken, Germany; Institute for Cardiovascular Regeneration, Goethe University, Frankfurt am Main, Germany; German Center for Cardiovascular Research, Partner site Rhein-Main, Frankfurt am Main, Germany
TEPIC funding source(s)
Supported by the German Federal Ministry of Education and Research in Germany (BMBF) [01DP17005,01KU1216A] and the Cluster of Excellence on Multimodal Computing and Interaction (DFG) [EXC248].

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