TEPITOPEpan statistics

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TEPITOPEpan specifications


Unique identifier OMICS_06757
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


Add your version


Unique identifier OMICS_06757
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for TEPITOPEpan

TEPITOPEpan in publications

PMCID: 5851651
PMID: 29499035
DOI: 10.1371/journal.pcbi.1005983

[…] pre-calculated, does not have an easy ilp representation. prediction methods must be directly incorporate into the ilp to approximate the immunogenicity of the current mutant s′. therefore, we use tepitopepan [], a linear hla-epitope affinity prediction method, as internal prediction engine since it has been demonstrated to have good predictive power and can be easily integrated into the ilp […]

PMCID: 5320590
PMID: 28348866
DOI: 10.1099/mgen.0.000071

[…] at most 1.8 s per peptide per cpu; this then has to be repeated for each allele., two mhc class ii binding-prediction methods that fit the speed and accuracy requirements were used in this study:, tepitopepan () is a position-specific scoring matrix (pssm)-based algorithm (). it uses 11 scoring matrices derived from combinatorial competitive binding assays on 11 hla-dr alleles (). this method […]

PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] peptide binding groove into account []. in 2005, zhang and colleagues published multipred [], one of the first pan-specific predictors. other pan-specific methods are netmhcpan [], pick-pocket [], tepitopepan [], adt [], unitope [] and kiss []. multi-pred trains one predictor per super-class (alleles with similar binding properties), whereas pickpocket and tepitopepan calculate the binding […]

PMCID: 4570239
PMID: 26370412
DOI: 10.1186/s12859-015-0724-8

[…] applied to develop tepitope, an algorithm for prediction of peptide ligands to 51 hla class ii alleles with known pocket residues [] and then extended to any hla-dr molecules with similar pockets (tepitopepan) []. a similar method has also been used in the pickpocket algorithm for mhc class i prediction []. whereas tepitopepan uses pocket profiles from tepitope, pickpocket generates binding […]

PMCID: 3908610
PMID: 24565049
DOI: 10.1186/1477-5956-11-S1-S15

[…] approaches. meanwhile, the method performs comparably to the tepitope and netmhciipan2.0 approaches in identifying hla-dr epitopes and ligands, and it performs significantly better than tepitopepan in the identification of hla-dr ligands and multirta in identifying hla-dr t cell epitopes., the proposed approach owa-pssm is fast and robust in identifying ligands, epitopes and binding […]

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TEPITOPEpan institution(s)
School of Computer Science and Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, China

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