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TFmiR specifications

Information


Unique identifier OMICS_08480
Name TFmiR
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Volkhard Helms

Publication for TFmiR

TFmiR citations

 (4)
library_books

Network analysis based on TCGA reveals hub genes in colon cancer

2017
PMCID: 5611503
PMID: 28947883
DOI: 10.5114/wo.2017.68622

[…] the core region was identified with mcode (molecular complex detection) [], a cytoscape plugin. mcode can detect densely connected regions in large protein-protein interaction networks., tfmir was used (http://service.bioinformatik.uni-saarland.de/tfmir) to identify the tfs that might regulate these differentially expressed genes and mirnas and to construct a tf-mirna-gene network. […]

library_books

Methods of MicroRNA Promoter Prediction and Transcription Factor Mediated Regulatory Network

2017
Biomed Res Int
PMCID: 5474535
PMID: 28656148
DOI: 10.1155/2017/7049406

[…] mirnas are two key elements in the regulation of genes. the regulatory relations, tf-mirna-target gene, are extremely complex, but they play an important role in pathogenic mechanism of diseases. tfmir is a web server to collect the coregulatory networks of disease-specific tfs and mirnas []. it integrates genome-wide transcriptional and posttranscriptional regulatory interactions on human […]

library_books

Linking Hematopoietic Differentiation to Co Expressed Sets of Pluripotency Associated and Imprinted Genes and to Regulatory microRNA Transcription Factor Motifs

2017
PLoS One
PMCID: 5215400
PMID: 28052084
DOI: 10.1371/journal.pone.0166852

[…] were compiled from the regulatory databases listed in []., the integrated association between the lineage markers and the enriched mirnas were compiled from the regulatory databases of the murine tfmir webserver []. all molecular interactions that are supported either by experimental and/or by predicted evidences were considered in this analysis. next, 3-node ffl motifs (tf-mirna […]

library_books

A microRNA molecular modeling extension for prediction of colorectal cancer treatment

2015
BMC Cancer
PMCID: 4470004
PMID: 26084510
DOI: 10.1186/s12885-015-1437-0

[…] into a data array (mirt) (with ensembl-id as key; mirna-id and references (pubmed) as value); for example, mirt[ensg00000236342] = (mir-1238, 17964270).convert the transmir data into a data array (tfmir) (with mir-id as key; ensembl-id, transcriptional regulation, references (pubmed) as value); for example, tfmir[mir-223] = (ensg00000159216, repression, 17996649).divide the nsaid model (xml […]


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TFmiR institution(s)
Center for Bioinformatics, Saarland University, Saarbrucken, Germany

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