THE-DB statistics

Tool stats & trends

Looking to identify usage trends or leading experts?


THE-DB specifications


Unique identifier OMICS_31866
Alternative name Threading Hard and Easy protein DataBase
Restrictions to use None
Database management system MySQL
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes


  • person_outline Justin Diamond

Publication for Threading Hard and Easy protein DataBase

THE-DB citations


SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic mice

PMCID: 5921754
PMID: 29703207
DOI: 10.1186/s12933-018-0708-x

[…] to analyze fecal samples from each mouse. PCoA and hierarchical clustering by Ward’s linkage of these visualizations suggest clustering of microbiota based on mouse genotype (Con vs Db groups), with the Db + dapa animals clustering as a subset within the Db group (Fig. a; PCoA: R2 = 0.27488; p < 0.001). Hierarchical clustering of the Db and Db-dapa groups was incomplete, with one sub-cluster cont […]


Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

Cell Rep
PMCID: 5908250
PMID: 29590614
DOI: 10.1016/j.celrep.2018.03.001

[…] P6-XT22). WNV-specific CD8+ T cells were stained using an Alexa-647 tetramer for the NS4B peptide as described previously (). ZIKV-specific CD8+ T cells were stained using an APC-labeled tetramer for the Db-restricted envelope protein peptide IGVSNRDFV (). Data were collected on a BD LSRII flow cytometer and analyzed using FlowJo software (Treestar, Inc.).Isolation of T cells and adoptive cell tra […]


On the Deployment and Noise Filtering of Vehicular Radar Application for Detection Enhancement in Roads and Tunnels

PMCID: 5877373
PMID: 29534483
DOI: 10.3390/s18030837

[…] he coordinate information (Range, Lat-Distance) of vehicle i to the user along with an accident judgment message. After an accident alarm, the corresponding information is recorded in the database in the “DB storage” component. […]


Identifying RNA splicing factors using IFT genes in Chlamydomonas reinhardtii

Open Biol
PMCID: 5881031
PMID: 29514868
DOI: 10.1098/rsob.170211

[…] 20). Thus, this SNP is tightly linked to the mutant phenotype. Figure 4.By RT-PCR, a single band from IFT121 exons 20–23 is amplified in wild-type cells (b, band A), while two bands are amplified in the db35-1 mutant (b, ift121-2). Sanger sequencing indicates the larger band (band B) contains intron 21 (electronic supplementary material, figure S4A) and the smaller band (band C) contains a trunca […]


Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells

PMCID: 5834638
PMID: 29500414
DOI: 10.1038/s41419-018-0396-1

[…] sites were located within genic and intergenic regions, respectively (Fig. ). Using Venny on DB sites with at least a two-fold change, a p-value < 0.05, and a FDR < 0.05, we found that nearly 41% of the DB sites mapped in the TSS, promoter, exons and introns regions of 903 genes, while very few peaks were specific to a single genomic region (Fig. ). The promoter region was defined as ±1 Kbp of th […]


Market Integration Predicts Human Gut Microbiome Attributes across a Gradient of Economic Development

PMCID: 5829308
PMID: 29507896
DOI: 10.1128/mSystems.00122-17

[…] RDA) () and permutational analysis of variance (PERMANOVA) (). These analyses reveal that house modernity is significantly associated with gut microbiome composition. We included participant region in the db-RDA analysis as a “Condition” variable, which means that its variance is “partialled out” by the analysis before considering the significance of the other variables.Finally, a multiple correlat […]


Looking to check out a full list of citations?

THE-DB institution(s)
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA; Department of Bioinformatics, Boston University, Boston, MA, USA
THE-DB funding source(s)
Supported by the National Institute of General Medical Sciences (GM083107, GM116960); National Science Foundation (DBI1564756).

THE-DB reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review THE-DB