An open database listing known adverse drug reactions with Human leukocyte antigens (HLA) alleles. The HLA-ADR has been implemented within the wider Allele Frequency Net Database (AFND), which stores large collections of data on the allele and haplotype frequencies for healthy, worldwide populations, as well as modules for exploring immunogenetic disease associations. HLA-ADR provides a resource that not only facilitates meta-analyses but also enables users to further their investigations by using resources available with the main AFND website, e.g. on the incidence of particular HLA alleles/haplotypes in healthy worldwide populations.
Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine Institute of Integrative Biology; Liverpool Reviews and Implementation Group Hesketh Centre, Mersey Care NHS Trust, Southport, UK; Center for Biomedical Research, Faculty of Medicine, Autonomous University of Coahuila, Torreon, Mexico; Human and Medical Genetics, Institute of Biological Sciences, Federal University of Para, Tucuruı, Brazil; Transplant Immunology Laboratory, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK; Institute of Infection and Global Health, University of Liverpool, Liverpool, UK