The Lair specifications


Unique identifier OMICS_12067
Name The Lair
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Allowed
Maintained Yes


  • person_outline Lior Pachter

Publication for The Lair

The Lair citations


The structure of a LAIR1 containing human antibody reveals a novel mechanism of antigen recognition

PMCID: 5459573
PMID: 28527239
DOI: 10.7554/eLife.27311.012
call_split See protocol

[…] nd a human monoclonal antibody Fab fragment similar to MGD21 (pdb: 3DIF, ()) separated into two files containing the variable and the constant regions, as search models. This identified two copies of the LAIR1-containing Fab fragment in the asymmetric unit of the antibody. Refinement and rebuilding was completed using Buster () and Coot () respectively. To determine the effect of the LAIR1 insert […]


Loss of Heterozygosity and Copy Number Alterations in Flow Sorted Bulky Cervical Cancer

PLoS One
PMCID: 3706587
PMID: 23874418
DOI: 10.1371/journal.pone.0067414

[…] n at the default settings of the DNAcopy R package . For each tumor, first the signal intensity of each chromosome was segmented, followed by a sub-segmentation of the previously obtained segments of the LAIR . By combining the continuous CN (signal intensity) and the LAIR value of a segment with the sample DNA index measured by flow cytometry, we developed a new calling method that assigns an all […]

The Lair institution(s)
Department of Computer Science, UC Berkeley, Berkeley, CA, USA; Department of Computer Science, University of Michigan, Ann Arbor, MI, USA; Innovative Genomics Initiative, UC Berkeley, Berkeley, CA, USA; Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, University of Iceland, Reykjavík, Iceland; Departments of Mathematics and Molecular & Cell Biology, UC Berkeley, Berkeley, CA, USA

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