Molecular dating of phylogenetic trees is a growing discipline using sequence data to co-estimate the timing of evolutionary events and rates of molecular evolution. All molecular-dating methods require converting genetic divergence between sequences into absolute time. Source…
TipDate
Web

TipDate

Uses sequences that have been isolated at different dates to estimate their…

Uses sequences that have been isolated at different dates to estimate their rate of molecular evolution. The program provides a maximum likelihood estimate of the rate and also the associated date of…

Physher
Desktop

Physher

A maximum likelihood-based method for estimating evolutionary rates and…

A maximum likelihood-based method for estimating evolutionary rates and divergence times from genetic data. The simplest model assumes that the substitution rate is constant over the whole phylogeny…

DAMBE
Desktop

DAMBE Data Analysis for Molecular Biology and Evolution

A comprehensive and user-friendly software workbench for data analysis in…

A comprehensive and user-friendly software workbench for data analysis in molecular biology and evolution. It features a variety of analytical functions for descriptive and comparative sequence…

BEAST
Desktop

BEAST Bayesian Evolutionary Analysis by Sampling Trees

A cross-platform program for Bayesian phylogenetic analysis of molecular…

A cross-platform program for Bayesian phylogenetic analysis of molecular sequences. BEAST estimates rooted, time-measured phylogenies using strict or relaxed molecular clock models. It can be used as…

PAML
Desktop

PAML Phylogenetic Analysis by Maximum Likelihood

A package of programs for phylogenetic analyses of DNA and protein sequences…

A package of programs for phylogenetic analyses of DNA and protein sequences using maximum likelihood (ML). PAML may be used to compare and test phylogenetic trees, but their main strengths lie in…

r8s
Desktop

r8s

Uses parametric, nonparametric and semiparametric methods to relax the…

Uses parametric, nonparametric and semiparametric methods to relax the assumption of constant rates of evolution to obtain better estimates of rates and times. r8s permits users to convert results to…

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