TiSAn statistics

To access cutting-edge analytics on consensus tools, life science contexts and associated fields, you will need to subscribe to our premium service.

Subscribe
info

Citations per year

Citations chart
info

Popular tool citations

chevron_left SNP/SNV annotation chevron_right
Popular tools chart
info

Tool usage distribution map

Tool usage distribution map
info

Associated diseases

Associated diseases

TiSAn specifications

Information


Unique identifier OMICS_18663
Name TiSAn
Alternative name Tissue-Specific Annotation
Software type Framework/Library, Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages R
License MIT License
Computer skills Advanced
Stability Stable
Maintained Yes

Download


Versioning


Add your version

Maintainer


  • person_outline Jacob Michaelson <>

Publication for Tissue-Specific Annotation

TiSAn in publications

 (7)
PMCID: 5805369
PMID: 29377896
DOI: 10.1371/journal.pgen.1007186

[…] we randomly selected 10 non-adjacent blocks as causal blocks and we randomly selected 20% snps inside these causal blocks to be causal snps (i.e. a total of 200 causal snps). we then simulated ten tissue-specific annotation sets, each with two annotations, which are simulated to correlate with snp causality []. specifically, the annotation values for the non-causal snps are sampled […]

PMCID: 5138592
PMID: 27922122
DOI: 10.1038/srep38588

[…] therefore they appear to be involved in more biological processes. this bias is present in any manually annotated pathway or biological database. as not all proteins listed in signalink 2 had tissue-specific annotation, we also conducted an analysis incorporating the unannotated proteins to every tissue (generating potential false positives with lesser known proteins but decreasing false […]

PMCID: 4772325
PMID: 26926147
DOI: 10.1186/s12864-016-2482-z

[…] expression patterns (wilcoxon p < 10−8). this consistency is striking given that the rna-seq data includes information about later embryonic stages not assayed in the imaging data. thus, known tissue-specific annotation and expression patterns support the idea that genes which occur in a given cluster are expressed in a similar set of embryonic cells., we further validated the clusters […]

PMCID: 4764260
PMID: 26901046
DOI: 10.1371/journal.pgen.1005875

[…] the association. as an example, the enrichment for ldl level-associated snps is 9.1-fold higher among snps predicted to affect hnf4 binding sites than in a background model already including tissue-specific annotation., a large fraction of genetic variants that have been associated with complex traits are found outside of protein coding genes and likely affect gene regulation. many […]

PMCID: 4327067
DOI: 10.3390/s150101106

[…] steven j.thoonen, g.thouand, geraldthoury, mathieutian, fengchuntian, guiyuntian, wei-chengtian, yutidoni, emmanueletie, litiloca, marcotimmermann, dirktimotheou, steliostimpe, shannon jting, lena h.tisan, alintisch, ulriketisseyre, brunotittel, francktjin, swee chuantofighi, mohammadtognetti, alessandrotollefsen, dagtomarchio, oraziotomás, juantomasi, riccardotomažič, sašotomkiewicz, […]


To access a full list of publications, you will need to upgrade to our premium service.

TiSAn institution(s)
University of Iowa, Carver College of Medicine, Iowa City, IA, USA; Department of Psychiatry, Carver College of Medicine, Iowa City, IA, USA
TiSAn funding source(s)
Supported by NIH grants MH105527 and DC014489.

TiSAn reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review TiSAn