A web-searchable database which provides information on interaction maps of transcription factor (TF) and tissue-specific (TS) miRNAs from experimentally validated and predicted data. TSmiR covers 116 TS miRNAs, 101 transcription factors and 2,347 TF-miRNAs regulatory relations in 12 tissues. Furthermore, experimentally validated expression data of TF and TS miRNA was also collected. The user can use the “search-by keyword” or “search-by category” function to retrieve the TF-TS miRNA regulatory relations. In addition to browsing TSmiR, there is a “browse” button at the top of the web page which allows users to explore TSmiR by clicking 12 different tissues.