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TLINKAGE specifications


Unique identifier OMICS_09414
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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  • person_outline Jurg Ott <>

Publication for TLINKAGE

TLINKAGE in publications

PMCID: 3778050
PMID: 23785127
DOI: 10.1136/jmedgenet-2013-101713

[…] the identification of genes causing monogenic diseases, the failure of the gla design in di merits investigation. there exist at least three software packages that can do two-locus linkage analysis: tlinkage, superlink and genehunter-twolocus. most of the studies that used two-locus linkage analysis used genehunter-twolocus. the mathematical basis for two-locus linkage analysis is that the test […]

PMCID: 1866786
PMID: 16451609
DOI: 10.1186/1471-2156-6-S1-S149

[…] were identified using single-locus models from previous investigations. we investigated the genetic linkage, pattern of disease inheritance, and pair-wise genetic epistasis of these loci using the tlinkage program for two-disease-locus analysis., many human diseases, such as cancers and psychiatric disorders, are caused by more than one gene. analysis using two-locus methods is a logical […]

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TLINKAGE institution(s)
Department of Medicine, University of Michigan, Ann Arbor, USA

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