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- person_outline Gabor Tusnady
Publications for TOPDOM
The human transmembrane proteome
[…] evidence level is the Experiment level, when the 3D structures of the protein itself or of homologous proteins are not known, but some molecular biology experiments were made. Entries are marked with TOPDOM evidence level, if bioinformatic evidences can be found that can be used as a strong argument to define the topology of the full protein or some parts of it. The experimental topology data is c […]
Reptation Induced Coalescence of Tunnels and Cavities in Escherichia Coli XylE Transporter Conformers Accounts for Facilitated Diffusion
[…] amino acids A, G, P, V, or C to produce the distributions. The EMBOSS utility ‘Shuffleseq’ generated the randomised sets of data. Similar searches were done in the database for transmembrane proteins TOPDOM. http://topdom.enzim.hu. (Tusnády et al. ). […]
Structural fragment clustering reveals novel structural and functional motifs in α helical transmembrane proteins
[…] embrane proteins. There are no comprehensive studies, to our knowledge, that focus on functional/structural motifs in transmembrane proteins. Among recent studies on transmembrane protein motifs, the TOPDOM database  collects domains and transmembrane protein sequence motifs from different motif databases and organizes them by their location in the protein with respect to the lipid layer.In the […]
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