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Toxicogenomic tools

Toxicogenomics focuses on assessing the safety of compounds using gene expression profiles. Gene expression signatures from large toxicogenomics databases are expected to perform better than small databases in identifying biomarkers for the…
CTD
Dataset

CTD Comparative Toxicogenomics Database

Provides information about interactions between environmental chemicals and…

Provides information about interactions between environmental chemicals and gene products and their relationships to diseases. Chemical-gene, chemical-disease and gene-disease interactions manually…

CEBS
Dataset

CEBS Chemical Effects in Biological Systems

Compiles individual and summary animal data from the National Toxicology…

Compiles individual and summary animal data from the National Toxicology Program (NTP) testing program and other depositors into a single electronic repository. CEBS contains over 11000 test articles…

BMDExpress…
Desktop
Web

BMDExpress Data Viewer

A web-based application for visualizing and graphing BMDExpress output files.…

A web-based application for visualizing and graphing BMDExpress output files. BMDExpress applies BMD modeling to transcriptomic datasets to identify transcriptional BMDs. Through our case studies, we…

MARCARviz
Web

MARCARviz

Allows simplified analysis of the data sets used and generated during the…

Allows simplified analysis of the data sets used and generated during the MARCAR project. Thus, it helps to identify potential biomarkers helping early detection of tumor formation among large sets…

Open TG-GATEs
Dataset
diXa
Dataset

diXa Data Infrastructure for Chemical Safety Assessment

A robust and sustainable infrastructure storing toxicogenomics data. A central…

A robust and sustainable infrastructure storing toxicogenomics data. A central data warehouse is connected to a portal with links to chemical information and molecular and phenotype data. diXa is…

SEGEL
Dataset

SEGEL Smoking Effects on Gene Expression of Lung

An online web server for easy and fast visualization of smoking effects on…

An online web server for easy and fast visualization of smoking effects on human lung gene expression. SEGEL integrates 362 samples collected from eight public expression microarray data sets from…

ToxDB
Dataset

ToxDB

A resource that analyzes drug-induced gene expression changes at the pathway…

A resource that analyzes drug-induced gene expression changes at the pathway level. We have collected 2694 pathway concepts and computed numerical response scores of these pathways for 437 drugs and…

ChemDIS
Web

ChemDIS

Provides enrichment analysis tools for identifying chemical-associated Gene…

Provides enrichment analysis tools for identifying chemical-associated Gene Ontology (GO), pathway (KEGG and Reactome) and Disease Ontology (DO and DOlite) based on a hypergeometric distribution.…

Toxygates
Web

Toxygates

An integrated platform for toxicogenomics data analysis. Toxygates combines a…

An integrated platform for toxicogenomics data analysis. Toxygates combines a large microarray dataset with the ability to fetch semantic linked data, such as pathways, compound-protein interactions…

LTMap
Web

LTMap Liver Toxicological Map

A web server for evaluating the potential liver toxicity based on genome-wide…

A web server for evaluating the potential liver toxicity based on genome-wide transcriptomics data.

BMDExpress
Desktop

BMDExpress

Analyzes dose-response data from microarray experiments. BMDExpress was…

Analyzes dose-response data from microarray experiments. BMDExpress was designed to perform a stepwise analysis on microarray data that combines benchmark dose (BMD) calculations with gene ontology…

MARCAR…
Web

MARCAR DataTools

Comprises set of tools for the visualization and analysis of microarray data…

Comprises set of tools for the visualization and analysis of microarray data sets obtained from short term carcinogenicity assays. MARCAR DataTools is available as an online tool which is part of the…

PharmIV
Web
Desktop

PharmIV Pharmacoepidemiology Instrumental Variable

A formula necessary to calculate power for instrumental variable analysis with…

A formula necessary to calculate power for instrumental variable analysis with a single binary instrument, binary exposure and continuous outcome in the context of pharmacoepidemiology. PharmIV has…

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