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RNA-Seq has effectively portrayed the transcriptional complexity in eukaryotes demonstrating the widespread transcription of lncRNAs in a diverse group of organisms. However, annotation of de-novo generated transcriptomes, remains a complex task requiring efficient management of large datasets.
(Musacchia et al., 2015) Annocript: a flexible pipeline for the annotation of transcriptomes able to identify putative long noncoding RNAs. Bioinformatics.