TRANSFAC statistics

Tool stats & trends

Looking to identify usage trends or leading experts?


TRANSFAC specifications


Unique identifier OMICS_00545
Restrictions to use License purchase required
Content license Commercial
Maintained Yes


  • person_outline Edgar Wingender

Publications for TRANSFAC

TRANSFAC citations


Systematic pan cancer analysis of somatic allele frequency

Sci Rep
PMCID: 5956099
PMID: 29769535
DOI: 10.1038/s41598-018-25462-0
call_split See protocol

[…] nnotation147/index.jsp). Pathogenicity was modeled using PolyPhen, CADD and FATHMM methods, and conservation was assessed based on GERP scores–. Transcription factor binding sites were analyzed using TRANSFAC 7.0. […]


Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy

Sci Rep
PMCID: 5940833
PMID: 29740045
DOI: 10.1038/s41598-018-25515-4

[…] base ( and the top 200 most abundant plasma proteins published previously. Functional annotation was performed by GO mapping using PANTHER ( and Biobase ( […]


Development of a computational promoter with highly efficient expression in tumors

BMC Cancer
PMCID: 5924487
PMID: 29703163
DOI: 10.1186/s12885-018-4421-7

[…] overexpress transgenes in the growing tumor area. Therefore, we designed the sequence of this promoter by bioinformatics. Figure  displays the flow chart describing the study design. According to the TRANSFAC database, 1624 genes with TF activity were identified. Subsequently, the Gene Ontology Consortium was used to define whether the activity of these TFs was associated with cell growth. Since a […]


Selection on the regulation of sympathetic nervous activity in humans and chimpanzees

PLoS Genet
PMCID: 5908061
PMID: 29672586
DOI: 10.1371/journal.pgen.1007311

[…] We searched the DHS2 sequences for transcription factor binding sites on the basis of the TRANSFAC [–] and JASPAR [–] databases by running FIMO [] at the P value threshold of 10-3. Our motif search was performed for the reference human and chimpanzee genomes (hg19 and panTro4) that carried […]


Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

Nat Commun
PMCID: 5906564
PMID: 29670077
DOI: 10.1038/s41467-018-03876-8
call_split See protocol

[…] 01A, SA Bioscience) designed for quantitative RT-PCR analysis were used to amplify the putative Stat3 binding site adjacent to the mouse Pax7 locus (Chr4: 139387970-139388390), identified via Biobase Transfac analysis (Biobase Corp. MA). The Stat3 occupancy was calculated as a ratio of the amplification efficiency of Stat3 ChIP over input chromatin. […]


Synergistic co regulation and competition by a SOX9 GLI FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions

PLoS Genet
PMCID: 5919691
PMID: 29659575
DOI: 10.1371/journal.pgen.1007346

[…] ing DNA elements. The Position Weight Matrices used for identification of SOX9 dimer and GLI binding elements were constructed from the SOX9 binding HMG core sequence and the GLI binding consensus in TRANSFAC database respectively. […]


Looking to check out a full list of citations?

TRANSFAC institution(s)
Department of Bioinformatics, Medical School, University of Göttingen, Goldschmidtstr Göttingen, Germany


star_border star_border star_border star_border star_border
star star star star star
Alvaro Sebastian's avatar image

Alvaro Sebastian

star_border star_border star_border star_border star_border
star star star star star
Probably one of the best annotated and curated resource of transcription factor binding preferences (sites and motifs). The free version (v7.0) is very limited and outdated (year 2005). If you want to have online access to the last version, the academic price is more than 1000$. There are other open access databases that can be considered before paying that price.