Translation efficiency prediction software tools | Synthetic biology
Translation initiation rate is a rate-limiting step in protein production from mRNA and is dependent on the sequence of the 5′-untranslated region and the start of the coding sequence. Translation rate calculators are programs that estimate protein translation rates based…
Web app
RBSDesigner RBSDesigner

RBSDesigner

Predicts the translation efficiency of existing mRNA sequences and designs…

Predicts the translation efficiency of existing mRNA sequences and designs synthetic ribosome binding sites (RBSs) for a given coding sequence (CDS) to yield a desired level of protein expression.…

Web app
UTR Designer UTR Designer

UTR Designer

A translation rate calculator. Users can apply this software tool in two…

A translation rate calculator. Users can apply this software tool in two different ways. First, UTR Designer can be used to predict the expression level of a particular mRNA sequence when given the…

Web app
UTR Library Designer UTR Library Designer

UTR Library Designer

A predictive combinatorial design method which systematically searches a large…

A predictive combinatorial design method which systematically searches a large combinatorial space of expression levels. UTR Library Designer accomplishes this by designing synthetic translation…

Desktop app
Web app
RiboMaker RiboMaker

RiboMaker

A web app for the computational design of conformation-based riboregulation.…

A web app for the computational design of conformation-based riboregulation. RiboMaker reads the sequence and structure specifications, which codify for a gene regulatory behaviour, and optimizes the…

Web app
Ribosome Binding Site… Ribosome Binding Site Calculator

RBS Calculator Ribosome Binding Site Calculator

A design method for predicting and controlling translation initiation and…

A design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA…

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