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Stores phylogenetic trees inferred from animal genomes. TreeFam is a database that aims at providing comprehensive gene evolution information and orthology assignments for animal gene families. The database also provides features to visualize gene family trees and to allow on-the-fly orthology prediction for a user-supplied sequence. It is a resource for studying animal gene families and orthologs and paralogs in animal genomes.

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TreeFam classification

TreeFam specifications

Restrictions to use:
Data access:
File download, Browse, Application programming interface
Community driven:
User data submission:
Not allowed

TreeFam support


  • Fabian Schreiber <>

Additional information


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Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, UK; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Funding source(s)

Supported by Wellcome Trust [WT077044/Z/05/Z], The Wellcome Trust [WT098051]; BBSRC [BB/I025506/1], European Molecular Biology Laboratory, European Community’s Seventh Framework Programme (FP7/2007-2013) [222664]. (‘Quantomics’).

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