TRIC statistics

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Associated diseases

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TRIC specifications


Unique identifier OMICS_12616
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Windows
Programming languages Python
Computer skills Advanced
Stability Stable
Source code URL
Maintained Yes



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  • person_outline Ruedi Aebersold <>

Publication for TRIC

TRIC in publications

PMCID: 5747350
PMID: 29226804
DOI: 10.1016/j.cels.2017.11.002

[…] this link, rpl14, yars, and gars all show a consistently reduced expression in several conditions in hek, hela, and huh7 cells (b). furthermore, all nine proteins from the chaperonin complex tric/cct showed decreased expression, whereas the levels of other chaperones were not consistently decreased (). phosphopeptides of several proteins involved in protein translation (rpl30, rps3, […]

PMCID: 5593115
PMID: 28604659
DOI: 10.1038/nbt.3908

[…] related to spectrum-centric site-localization applicable to dia data, e.g. dia-umpire,/luciphor, or swathprophetptm, but with a focus on consistent detection and quantification. this is useful for tric, which transfers the detection confidence across different runs based on the retention times and detection confidence of the candidate peak groups. if in a certain fraction of measurements, […]

PMCID: 5457488
PMID: 28575672
DOI: 10.1016/j.cell.2017.05.010

[…] human proteins with unique swiss-prot identities (). openswath first identified the peak groups from all individual swath maps at a target fdr = 1% and then aligned between swath maps using a novel tric (transfer of identification confidence) algorithm that was specifically developed for targeted proteomic data analysis (). the re-quantification feature in openswath was enabled […]

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TRIC institution(s)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland; Department of Genetics, Stanford University, Stanford, CA, USA; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy; Institute for Immunology, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany; PhD Program in Systems Biology, University of Zurich and ETH Zurich, Zurich, Switzerland; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; S3IT, University of Zurich, Zurich, Switzerland; Faculty of Science, University of Zurich, Zurich, Switzerland

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