Predicts Unique PPIs in Trypanosome (TPPIs) from the 3D structure of proteins involved in protein-protein interactions (PPI). Trypano-PPI is implemented as a web-server. The software predicts how a unique protein-protein complex in Trypanosome proteome is with respect to other parasites and host breaking new ground for antitrypanosome drug target discovery.
Department of Microbiology & Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain; Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, A Coruna, Spain
Trypano-PPI funding source(s)
Supported by contract sponsored by Xunta de Galicia (grant: Isidro Parga Pondal Program), the General Directorate of Scientific and Technologic Promotion of the Galician University System, Xunta de Galicia (grants: 2007/127 and 2007/144), and Carlos III Health Institute (grants: PIO52048 and RD07/0067/0005).