TSEMA specifications

Unique identifier:
Restrictions to use:
Computer skills:
Web user interface
Input data:
The initial input for the system are the two families of homologous proteins for which the user wants to predict the mapping. There is a set of advanced options to control the Monte Carlo algorithm which are intentionally blurred unless the user decides to enable them. For the two families of proteins, the user can either submit two phylogenetic trees (in Newick format) or two multiple sequence alignments in a format compatible with ClustalW. In the second case, the system generates the phylogenetic trees from the alignments using the neighbour joining algorithm implemented in ClustalW.

TSEMA support



  • Florencio Pazos <>


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National Center for Biotechnology (CNB-CSIC) C/Darwin, Cantoblanco, Madrid, Spain; National Bioinformatics Institute (INB), Barcelona Supercomputer Centre C/Jordi Girona, Barcelona, Spain; Department of Biochemistry and Molecular Biology, Biomolecular Structure and Modelling Unit, University College London, London, UK

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