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Tumor purity deconvolution software tools | Bisulfite sequencing data analysis

In recent years, whole genome bisulfite sequencing (WGBS) and reduced representation bisulfite sequencing (RRBS) have been increasingly used to profile the DNA methylation patterns between tumors and their normal counterparts, where differential methylated regions not only serve as important cancer biomarkers and therapeutic targets, but also provide insights to the mechanism of tumorigenesis and progression (Shen et al., 2005; Issa, 2007; Hon et al., 2012). Source text: Zheng et al., 2014.

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