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Tumor purity deconvolution software tools | Bisulfite sequencing data analysis

In recent years, whole genome bisulfite sequencing (WGBS) and reduced representation bisulfite sequencing (RRBS) have been increasingly used to profile the DNA methylation patterns between tumors and their normal counterparts, where differential…
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methylFlow
Desktop

methylFlow

Uses sequencing reads from high-throughput sequencing of bisulfite-converted…

Uses sequencing reads from high-throughput sequencing of bisulfite-converted DNA to reconstruct heterogeneous cell populations by assembling cell-specific methylation patterns. methylFlow is based on…

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MethylPurify
Desktop

MethylPurify

Uses regions with bisulfite reads showing discordant methylation levels to…

Uses regions with bisulfite reads showing discordant methylation levels to infer tumor purity from tumor samples alone. MethylPurify can identify differentially methylated regions (DMRs) from…

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