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Tumour neoantigen identification software tools | Whole-genome sequencing data analysis

Cancer immunotherapy has gained significant momentum from recent clinical successes of checkpoint blockade inhibition. Massively parallel sequence analysis suggests a connection between mutational load and response to this class of therapy. Methods…
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pVAC-Seq
Desktop

pVAC-Seq personalized Variant Antigens by Cancer Sequencing

A flexible, streamlined computational workflow for identification of…

A flexible, streamlined computational workflow for identification of personalized Variant Antigens by Cancer Sequencing (pVAC-Seq) that integrates tumor mutation and expression data (DNA- and…

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CloudNeo
Desktop

CloudNeo

Provides a cloud based analysis pipeline for tumor neoantigen detection.…

Provides a cloud based analysis pipeline for tumor neoantigen detection. CloudNeo uses Docker containers to execute the tasks in workflow. It allows users to realize advantages of cloud analysis,…

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INTEGRATE-Neo
Desktop

INTEGRATE-Neo

A neoantigen discovery pipeline to identify gene fusions in prostate cancers…

A neoantigen discovery pipeline to identify gene fusions in prostate cancers that may produce neoantigens. INTEGRATE-Neo, is comprised of the following steps: (i) gene fusion peptide prediction, (ii)…

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neoantigenR
Desktop

neoantigenR

Identifies peptide epitope candidates. neoantigenR is an R package that…

Identifies peptide epitope candidates. neoantigenR is an R package that facilitates the identification of disease/sample specific protein isoforms using both short read or long read high-throughput…

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TSNAD
Desktop

TSNAD

Identifies cancer somatic mutations following the best practices of the genome…

Identifies cancer somatic mutations following the best practices of the genome analysis toolkit (GATK) from the genome/exome sequencing data of tumor-normal pairs. TSNAD is an integrated software…

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MuPeXI
Web
Desktop

MuPeXI Mutant peptide extractor and informer

Identifies tumor-specifc peptides and assess their potential to be…

Identifies tumor-specifc peptides and assess their potential to be neo-epitopes. MuPeXI is based on priority score intended to rank peptides according to likelihood of eliciting a T cell response. It…

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