UCNEbase specifications


Unique identifier OMICS_09641
Name UCNEbase
Restrictions to use None
Maintained Yes


  • person_outline Philipp Bucher

Publications for UCNEbase

UCNEbase citations


Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion

PLoS Comput Biol
PMCID: 5333799
PMID: 28253259
DOI: 10.1371/journal.pcbi.1005341

[…] Pre-miRNAs were obtained from miRBASE []. Disease-associated SNPs were obtained from the GWAS database ( Ultraconserved regions were obtained from UCNEbase []. For human positive and negative masks we used DNaseI hypersensitive sites identified through genome-wide profiling in 125 diverse cell and tissue types by the ENCODE consortium [] and Rep […]


Kiwi genome provides insights into evolution of a nocturnal lifestyle

Genome Biol
PMCID: 4511969
PMID: 26201466
DOI: 10.1186/s13059-015-0711-4
call_split See protocol

[…] mino acid changes with signs of selection and specific for the kiwi were visualized in both sequenced individuals.Chicken UCNEs annotations were downloaded from the ultra-conserved non-coding element UCNEbase []. Orthologous regions in Apteryx mantelli and Struthio camelus, Tinamus guttatus, Tyto alba, Antrostomus carolinensis genomes, downloaded from GigaDB [], and birds from Ensembl 74 [] Ficedu […]

UCNEbase institution(s)
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology (EPFL); Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland
UCNEbase funding source(s)
The Swiss National Science Foundation [PDFM33-120719]

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