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Gathers information about human neutral and disease variants of membrane proteins. MutHTP is a database for understanding the influence of mutations in membrane proteins and developing prediction methods. It provides information on each mutation and its chromosomal location, origin, gene name, UniProt ID, PDB code, location of the mutant with respect to the membrane protein topology (transmembrane domains vs exposed loops), neighbouring residues of the mutant, diseases associated with the mutation, disease classes and the source databases.
OPM DB / Orientation of Proteins in Membranes database
Allows users to explore the protein-membrane systems of the Orientations of Proteins in Membranes (OPM) built and equilibrated using High-Throughput Molecular Dynamics (HTMD). OPM-DB simulates the dataset in both CHARMM and AMBER force fields. It permits users to view trajectories, Root-Mean-Square-Deviation (RMSD) plots as well as download the final equilibrated structures for further simulation. The repository is part of the PlayMolecule platform.
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