bookmark Caleydo Facilitates understanding of the interconnection of pathways. Caleydo enables a non-distracting relation to gene expression data. It is based on simultaneous consideration of gene expression information and pathways. It allows to explore relationships between multiple, handcrafted pathways, and relationship of pathways to actual measurements of gene expression regulation directly. It can improve the process of understanding the complex network of pathways and the individual effects of gene expression regulation considerably.