Gives access to many free software tools for sequence analysis. EMBOSS aims to serve the molecular biology community. It permits the creation and the release of software in an open source spirit. This tool is useful for sequence analysis into a seamless whole. It is free of charge and is available in open source.
Investigates protein and peptides sequences for producing numerical feature representation schemes. iFeature assists users in establishing machine-learning models and predictions as well as in handling feature producing. The program gathers more than ten algorithms dedicated to feature selection, clustering and dimensionality reduction. It is also implemented through a web application that computes protein and peptides descriptors compiled in the package.
Allows to study the biomechanical properties by interactively highlighting rigidity, flexibility, and allosteric effects. BioSpring is a software that implements a method based on a spring network model adding non-bonded interactions. This model is guided by an electrostatic map, and it uses advanced human interaction techniques dedicated to interactive molecular modeling. This application is also designed to help a user in the complex task of modeling large biomolecular complexes.
Makes comparison between two sets of aligned sequences. Shannon Entropy-Two is able to estimate if there is greater variability in one set relative to the other. It can randomize the combined sequence sets either with replacement or no replacement. This tool enables the re-computation of the entropies for two random data sets broken down into sets of the same size as the original two.
Determines the variation in DNA and protein sequence alignments. Shannon Entropy-One employs phylogenetics into Shannon entropy to proceed. It can compute the entropy at each position in one input sequence set. This tool can calculate the relative variation in different positions or regions of an aligned gene or protein.
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