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Unimod specifications


Unique identifier OMICS_06202
Name Unimod
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes

Publication for Unimod

Unimod citations


The NISTmAb tryptic peptide spectral library for monoclonal antibody characterization

PMCID: 5916550
PMID: 29425077
DOI: 10.1080/19420862.2018.1436921

[…] was sodium; 59 sodiated ions were identified. Examination of adduct fragmentation behavior showed that the metal atom did not generally appear to be localized at specific amino acids as suggested by Unimod. Rather, metal atoms appear to be bound to multiple amino acids in a peptide sequence, effectively impeding fragmentation in the relevant region, and reducing their “scores” from sequence searc […]


Large scale intact glycopeptide identification by Mascot database search

Sci Rep
PMCID: 5795011
PMID: 29391424
DOI: 10.1038/s41598-018-20331-2

[…] he world and easily adaptable for glycopeptide analysis as described here. The necessary changes to establish Mascot for glycopeptide analysis are simply done by defining the letters (O, J, U) in the unimod.xml file (Supplementary Fig. 1) and updating the Mascot server with the glycoprotein database. The linear glycan sequences as well as the script to prepare a custom glycoprotein database are pr […]


Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae

PMCID: 5358975
PMID: 28287394
DOI: 10.7554/eLife.23816.019

[…] revisiae protein database (Jul-2013, 6629 entries) supplemented with the trypsin sequence and common protein contaminant sequences was employed. In the software algorithm, all modifications listed in UniMod are searched simultaneously with the tolerance specified as ±0.05 Da for peptides and MS/MS fragments (). ProteinPilot automatically clusters identified proteins into protein groups sharing com […]


Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future

Chem Res Toxicol
PMCID: 5241710
PMID: 27989119
DOI: 10.1021/acs.chemrestox.6b00366

[…] ed to peptides can be searched by online tools to facilitate the identification of putative adducted masses to Alb, including The National Institute of Standards (http://webbook.nist.gov/chemistry/); Unimod protein modifications for mass spectrometry (www.unimod.org); The Association for Biomedical Resource Facilities (https://abrf.org/delta-mass); The Human Metabolome Database (www.hmdb.ca/metabo […]


Maintenance of electrostatic stabilization in altered tubulin lateral contacts may facilitate formation of helical filaments in foraminifera

Sci Rep
PMCID: 4990898
PMID: 27539392
DOI: 10.1038/srep31723

[…] ng the Joint Center for Structural Genomics’ Quality Control Check version 3.1 (http://smb.slac.stanford.edu/jcsg/QC/). A meta-assessment was carried out using MetaMQAP (https://genesilico.pl/toolkit/unimod?method=MetaMQAPII) to obtain an MetaMQMAPII score. Both the Molprobity and MetaMQMAPII scores reflect the expected value of the X-ray resolution in Å given the scores for the model. All these a […]


Cleaning out the Litterbox of Proteomic Scientists’ Favorite Pet: Optimized Data Analysis Avoiding Trypsin Artifacts

J Proteome Res
PMCID: 4820788
PMID: 26938934
DOI: 10.1021/acs.jproteome.5b01105

[…] ed. Examples for the latter are the (discontinued) OMSSA engine, Andromeda (MaxQuant), Sequest, and MS Amanda. Sequest, for example, does in our hands not accept additional amino acids defined in the unimod.xml, and MaxQuant in its current version has no option to add non-natural amino acids. In our opinion, it would be useful to either include a special letter for the omnipresent case of dimethyl […]


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Unimod institution(s)
Matrix Science Ltd, London, UK

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